Francisco Wanderley Garcia Paula-Silva Selected Research

Periapical Periodontitis (Apical Periodontitis)

2/2022	Gene expression data of inflammatory mediators in apical periodontitis in 129 (wild type) and 5-lipoxygenase knockout mice.
11/2021	Effect of non-steroidal anti-inflammatory drugs on pulpal and periapical inflammation induced by lipopolysaccharide.
7/2021	Osteoclast formation, inflammation, and matrix metalloproteinase-9 are downregulated in bone repair following root canal treatment in dogs teeth.
4/2020	Effects of 5-lipoxygenase gene disruption on inflammation, osteoclastogenesis and bone resorption in polymicrobial apical periodontitis.
1/2020	Root canal contamination or exposure to lipopolysaccharide differentially modulate prostaglandin E 2 and leukotriene B 4 signaling in apical periodontitis.
6/2019	Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage.
7/2018	Immunohistochemical and mRNA expression of RANK, RANKL, OPG, TLR2 and MyD88 during apical periodontitis progression in mice.
3/2016	Dual Role of 5-Lipoxygenase in Osteoclastogenesis in Bacterial-induced Apical Periodontitis.
9/2011	Microbial culture and checkerboard DNA-DNA hybridization assessment of bacteria in root canals of primary teeth pre- and post-endodontic therapy with a calcium hydroxide/chlorhexidine paste.
1/2011	Root canal treatment of an immature dens invaginatus with apical periodontitis: a case report.

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Francisco Wanderley Garcia Paula-Silva Research Topics

Disease

12	Inflammation (Inflammations) 02/2022 - 02/2010
11	Periapical Periodontitis (Apical Periodontitis) 02/2022 - 02/2010
4	Bone Resorption 02/2022 - 03/2016
2	Root Resorption 12/2021 - 03/2021
2	Infections 08/2021 - 01/2012
2	Wounds and Injuries (Trauma) 01/2017 - 08/2010
1	Infertility (Sterility) 01/2022
1	Pulpitis 11/2021
1	Septic Shock (Toxic Shock Syndrome) 06/2021
1	Ankylosis 03/2021
1	Tooth Resorption 03/2021
1	Respiratory Insufficiency (Respiratory Failure) 09/2020
1	Hepatic Insufficiency 09/2020
1	Rare Diseases (Rare Disease) 09/2020
1	Jeune syndrome 09/2020
1	Skin Ulcer 01/2017
1	Cicatrix (Scar) 01/2017
1	Ulcer 01/2017
1	Facial Paralysis (Facial Palsy) 04/2014
1	Trismus (Lockjaw) 04/2014
1	Second Primary Neoplasms (Neoplasms, Second) 04/2014
1	Neoplasms (Cancer) 04/2014
1	Medulloblastoma 04/2014
1	Bites and Stings (Sting) 01/2014
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2014
1	Coinfection 09/2011
1	Necrosis 08/2010

Drug/Important Bio-Agent (IBA)

4	Calcium HydroxideIBA 07/2021 - 02/2010
3	EnzymesIBA 02/2022 - 01/2020
3	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 02/2022 - 03/2016
2	Leukotriene B4IBA 01/2022 - 01/2020
2	LipopolysaccharidesIBA 11/2021 - 01/2020
2	Messenger RNA (mRNA)IBA 07/2018 - 01/2017
2	Pemetrexed (MTA)FDA Link 07/2017 - 01/2011
1	CytokinesIBA 02/2022
1	ChemokinesIBA 02/2022
1	SolventsIBA 01/2022
1	EmulsionsIBA 01/2022
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2021
1	Indomethacin (Indometacin)FDA LinkGeneric 11/2021
1	Celecoxib (Celebrex)FDA Link 11/2021
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 11/2021
1	caffeic acidIBA 08/2021
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2021
1	Alkaline PhosphataseIBA 07/2021
1	tartaric acid (tartrate)FDA Link 07/2021
1	CurcuminIBA 06/2021
1	Photosensitizing Agents (Photosensitizers)IBA 06/2021
1	PeriostinIBA 03/2021
1	Denosumab FDA Link 03/2021
1	Retinaldehyde (Retinal)IBA 09/2020
1	ProstaglandinsIBA 01/2020
1	SuspensionsIBA 01/2020
1	Arachidonic Acid (Vitamin F)IBA 01/2020
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 06/2019
1	LipidsIBA 06/2019
1	Dinoprostone (PGE2)FDA Link 06/2019
1	Gutta-Percha (Guttapercha)IBA 07/2017
1	tricalcium silicateIBA 07/2017
1	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 01/2017
1	Peroxidase (Myeloperoxidase)IBA 01/2017
1	lipoxin A4IBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 07/2016
1	Tartrate-Resistant Acid PhosphataseIBA 03/2016
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2015
1	PPAR gammaIBA 01/2015
1	VenomsIBA 01/2014
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2012
1	Ointments (Pastes)IBA 09/2011
1	ChlorhexidineIBA 09/2011
1	hydroxide ionIBA 08/2010
1	Matrix Metalloproteinases (MMPs)IBA 02/2010

Therapy/Procedure

2	Root Canal Therapy 07/2021 - 02/2010
1	Microspheres (Microsphere) 01/2022
1	Tooth Replantation 12/2021
1	Therapeutics 11/2021
1	Replantation 03/2021
1	Radiotherapy 04/2014
1	Drug Therapy (Chemotherapy) 04/2014
1	Acupuncture Points (Acupuncture Point) 04/2014
1	Lasers (Laser) 04/2014
1	Acupressure (Shiatsu) 04/2014
1	Aftercare (After-Treatment) 02/2010